Error .exe Not Valid — Mastercam X5

John had been using Mastercam X5 for years to design and manufacture parts for his small business. However, one day, when he tried to launch the software, he was greeted with an error message that read: "The .exe file is not a valid Win32 application."

Windows Registry Editor Version 5.00
[-HKEY_CURRENT_USER\Software\Microsoft\Windows\CurrentVersion\Explorer\FileExts\.exe]
[HKEY_CLASSES_ROOT\.exe]
@="exefile"
[HKEY_CLASSES_ROOT\exefile\shell\open\command]
@="\"%1\" %*"

A fellow user suggested that John try running the software as an administrator. John right-clicked on the Mastercam X5 icon and selected "Run as administrator," but the error message persisted. mastercam x5 error .exe not valid